Unspliced regulator
نویسندگان
چکیده
منابع مشابه
Unspliced regulator
A lthough most RNA splicing occurs in the nucleus, HAC1 and XBP1 mRNAs are spliced in the cytoplasm during ER stress. On page 565 , Yoshida et al. demonstrate that in the case of XBP1 both the unspliced and spliced RNAs produce functional proteins and together the proteins form a feedback system that controls the duration of the stress response. When unfolded proteins accumulate in the ER, sens...
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Acknowledgment I would like to thank everybody who helped me during my study and writing of this thesis. Special thanks goes to my supervisor Peter for being the most knowledgeable person I ever met and also for always supporting my funny ideas. Another great help with everything I had to do in the last years was Sonja. My family has been greatly supportive and patient. My working room mates, S...
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Tap has been proposed to play a role in general mRNA export and also functions in expression of RNA with retained introns that contain the MPMV CTE (constitutive transport element). Tap forms a functional heterodimer with NXT/p15. We have previously demonstrated that unspliced intron-containing CTE RNA is efficiently exported to the cytoplasm in mammalian cells. Here we show that Tap and NXT pr...
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In this paper, the dynamic simulation for a high pressure regulator is performed to obtain the regulator behavior. To analyze the regulator performance, the equation of motion for inner parts, the continuity equation for diverse chambers and the equation for mass flow rate were derived. Because of nonlinearity and coupling, these equations are solved using numerical methods and the results are ...
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Post-transcriptional control in both HIV-1 and HIV-2 is a highly regulated process that commences in the nucleus of the host infected cell and finishes by the expression of viral proteins in the cytoplasm. Expression of the unspliced genomic RNA is particularly controlled at the level of RNA splicing, export, and translation. It appears increasingly obvious that all these steps are interconnect...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2006
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1724iti3